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Obesity and Cancer Mechanisms: Tumor Microenvironment and Inflammation

There is growing evidence that inflammation is a central and reversible mechanism through which obesity promotes cancer risk and progression.

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Obesity and Cancer: Insights for Clinicians

The association of obesity with cancer, increasingly recognized in both lay and medical communities and underscored by the ongoing obesity epidemic, has stimulated a large body of research and led to calls for programs to minimize any potential impact of obesity on cancer

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Obesity and Breast Cancer Prognosis: Evidence, Challenges, and Opportunities

We reviewed the literature regarding overweight and obesity and breast cancer survival outcomes, overall and with regard to breast cancer subtypes, breast cancer therapies, biologic mechanisms, and possible interventions.

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Obesity and survival among women with ovarian cancer: results from the Ovarian Cancer Association Consortium

Observational studies have reported a modest association between obesity and risk of ovarian cancer; however, whether it is also associated with survival and whether this association varies for the different histologic subtypes are not clear. We undertook an international collaborative analysis to assess the association between body mass index (BMI), assessed shortly before diagnosis, progression-free survival (PFS), ovarian cancer-specific survival and overall survival (OS) among women with invasive ovarian cancer.

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Body Mass Index and Outcomes in Patients Who Receive Adjuvant Chemotherapy for Colon Cancer

Although several studies have established a link between obesity and colon cancer risk, little is known about the effect of obesity on outcomes after diagnosis. We investigated the association of body mass index (BMI) with outcomes after colon cancer in patients from cooperative group clinical trials.

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Body-Mass Index and Mortality in a Prospective Cohort of U.S. Adults

Body-mass index (the weight in kilograms divided by the square of the height in meters) is known to be associated with overall mortality. We investigated the effects of age, race, sex, smoking status, and history of disease on the relation between body-mass index and mortality.

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